We're bringing our brand-new Time-of-Flight Mass Spectrometer with us to sunny Anaheim, California for the 72nd annual ASMS Conference! Stop by Booth #500 to get an up-close look and bring your questions to our educated and eager team.
Meet the BTX Poster Presentations
The BTX is the newest iteration of LECO's Benchtop (or BT) GC-TOFMS series. For the past 8 years, the Pegasus BT series has proven reliability in labs for a diverse spectrum of investigators–including those in industries like Petroleum, Life Sciences, Flavor and Fragrance, Environmental, Pharmaceutical, Food Safety, and others.
The newly released Pegasus BTX retains the innovative StayClean® ion source, blinding fast full-spectrum acquisition rates, and five orders of linear dynamic range. A novel ion path and detector design delivers femtogram-level sensitivity in our smallest mass spectrometer yet. At LECO, technological innovations never jeopardize our commitment to instrument quality and robustness–that's why all new BTX systems include a two-year detector warranty.
Achieve trace-level detection with helium or hydrogen carrier gases.
Optimized deconvolution yields clean analyte spectra from dense matrix background.
The StayClean ion source requires no cleaning even after sustained heavy matrix exposure.
Collect full mass range data, even when performing targeted analyses.
LECO's stellar team of Applications Scientists work year-round with our next-level instruments to make new discoveries and explore the possibilities within targeted and non-targeted analyses. Learn more about their work by viewing the list of poster presentations below, and be sure to attend if you'll be at ASMS!
A new splitter makes simultaneous acquisition of accurate quantitative FID and qualitative TOFMS data possible throughout the GC temperature program. More accurate individual compound identification and group-type composition information is achieved using dual-detection GCxGC for sustainable alternatives to traditional petroleum fuels such as waste plastics-derived pyrolysis oils (WPPO), hydrotreated esters and fatty acids (HEFA), and synthesized iso-paraffins (SIP).
Monitoring hazardous chemicals, such as persistent organic pollutants (POPs), is challenging due to the large number of compounds with different physiochemical properties present in a wide range of concentrations in complex environmental matrices. It is critically import to develop rapid and robust screening methods.
Topical gels and ointments are challenging matrices for the analysis of leachables. Pairing novel sample preparation strategies with a non-targeted GC-TOFMS analysis workflow leveraging mass spectral deconvolution is demonstrated which provides the ability to effectively detect and identify both targeted and non-targeted compounds even in the presence of challenging matrix interferences.
Nepeta Cataria (Catnip), known for affecting feline behavior, is an essential oil rich in bioactive compounds that make it useful as an antioxidant, anti-inflammatory, anti-cancer, and antimicrobial material. However, Catnip essential oil continues to show promise for even more applications, so we developed a new analysis method to characterize this very complex plant that combines chromatographic separation with high-performance TOFMS.
Research into the prevalence of Per- and polyfluoroalkyl substances (PFAS) continues to grow due to concerns about their impact on human health. These materials are used in a wide variety of consumer products, and they accumulate over time in our environment. Regulatory control of these compounds has focused on the targeted analysis of a narrow quantity of PFAS classes, so in this study, we performed non-targeted analysis of PFAS-containing solutions using gas chromatography with time-of-flight mass spectrometry (GC-TOFMS).
Detection efficiency, fast response, and longevity are the critical attributes of ion detectors in TOFMS. The extension of a detector's lifetime is becoming especially important for the modern GC/GCxGC-TOFMS as improvements in ion transmission efficiency have increased the flux and rate of ions arriving at detectors. Adaptation of GC/GCxGC-TOFMS instrumentation for routine or long-term analysis is demanding a significant extension of an ion detector's lifetime. Combining all these requirements in a single design is the challenging task we took on.
Modern ion-optical design principles which allow gains in sensitivity and resolving power may inadvertently alter fragmentation patterns, which may in turn affect the reliability of automated comparisons against standard libraries. To evaluate the matching quality of the EI spectra generated by this multi-mode ionization source, we collected data from 207 diverse analytes in standards and 66 of those same analytes in spiked samples, then compared them against the NIST23 library.
Determining the aroma compounds of herbs and spices is important for many purposes in the flavor, fragrance, and food industry. Gas Chromatography (GC) and Time-of-Flight Mass Spectrometry (TOFMS) are well-suited for this type of non-target aroma profiling, as analytes of interest can be separated, identified, and discovered. In this work, dried thyme from different geographical locations was analyzed and compared.
LECO's Liz Humston-Fulmer will serve as co-chair of the ASMS Flavor, Fragrance and Footstuff Interest Group with David Schroeder (Kraft-Heinz) on Tuesday 4 June 2024, from 5:45 to 7:00 in Room 208AB.
The Flavor Fragrance and Foodstuff Workshop will cover a range of topics related to GC, MS, and data analysis tools that are relevant to these industries. There are a wide range of sample types and analysis objectives within this field, but many application goals are consistent and involve determining reliable identification of analytes and performing exploratory characterization and comparison of data from samples and sets of samples. Both of these topics will be covered in the workshop through application examples from panelists and open discussion.
One discussion topic will focus on approaches to identification and will include using acquired spectral information with library databases, using chromatography to improve separation and spectral quality, and connecting tentative identification with sensorial descriptions. High-resolution MS data will also be discussed as a support to library matches and as a path towards identifying analytes without library matches. A second discussion topic will focus on data analysis options to compare and characterize data from sets of samples and will include strategies for clustering, machine learning, and various software and modeling tools. Data characteristics, strategies, and software tools will be discussed.
The workshop will be interactive and will cover these topics through application demonstrations from a panel of speakers as well as through open discussion with the panel and attendees.